Publications

Update 22-JAN-2026

＊Corresponding author(s)

2025

  1. Sandra Vranic, Eri Watanabe, Kyoka Yamazaki, Takatsugu Wakahara, Kayoko Miyakawa, Sakie Takeuchi, Yurika Osada, Sahoko Ichihara, Wenting Wu, Cai Zong, Toshihiro Sakurai, Akira Sato, Yasushi Hara, Akihiko Ikegami, Yuya Terashima, Kouji Matsushima, Toshihiro Suzuki, Ryo Abe, Sonja Boland, Tran Lang, ＊Gaku Ichihara. Impact of surface functional group modification on cellular internalization and cytotoxicity of silica nanoparticles. Particle and Fibre Toxicology, in press. (IF=8.2 in 2024) DOI: https://doi.org/10.1186/s12989-025-00653-6
  2. #Kaede Tsuda, #Yoko Ogino, ＊Akira Sato. Anticancer sensitivities and biological characteristics of HCT116 cells resistant to the selective poly(ADP-ribose) glycohydrolase inhibitor. FEBS Open Bio, in press. (IF=2.3 in 2024) # equally contribution. DOI: 10.1002/2211-5463.70178
  3. Masato Suzuki, Takehiro Suzuki, Yoshio Nakano, Ken Matsumoto, Hitomi Manaka, Masahiro Komeno, Shoma Tamori, Akira Sato, Naoshi Dohmae, Kazunori Akimoto, Satoru Miyazaki, Takashi Suda, Toshihiko Toida, Keiko Kashiwagi, Kazuei Igarashi, Kyohei Higashi. Polyamines stimulate the protein synthesis of the initiation factor eIF5A2 participating in mRNA decoding distinct from eIF5A1. Journal of Biological Chemistry, 301(8), 110453, 2025. https://doi.org/10.1016/j.jbc.2025.110453 (IF=3.9 in 2024)  
  4. Haruka Uozumi, Shinpei Kawakami, Yuko Matsui, Sadao Mori, ＊Akira Sato. Passion fruit seed extract protects hydrogen peroxide-induced cell damage in human retinal pigment epithelium ARPE-19 cells. Scientific Reports, 15, 1715, 2025. https://doi.org/10.1038/s41598-025-85158-0. (IF=3.9 in 2024)

2024

  1. Chinatsu Kurasaka, Nana Nishizawa, Yoko Ogino, ＊Akira Sato. Anticancer sensitivity and biological aspect of 5-fluorouracil-resistant human colorectal cancer HCT116 cells in three-dimensional culture under high- and low-glucose conditions. Nucleosides, Nucleotides & Nucleic Acids, 43(8), 870-880, 2024. https://doi.org/10.1080/15257770.2024.2332414. (IF= 1.3 in 2024)
  2. Akira Kagawa, Akira Sato, Kimiko Makino, ＊Issei Takeuchi. Therapeutic effects of 30-nm cyclosporin A-loaded nanoparticles using PLGA-PEG-PLGA triblock copolymer for transdermal delivery in mouse models of psoriasis. Applied Sciences, 14(9), 3791, 2024. https://doi.org/10.3390/app14093791. (IF= 2.5 in 2024)
  3. Ryo Okamoto, Koki Toya, Yoko Ogino, ＊Akira Sato. Down-regulation of long noncoding RNA TP73-AS1 confers resistance to temozolomide in human glioblastoma cells. Nucleosides, Nucleotides & Nucleic Acids, 43(1), 86-98, 2024. https://doi.org/10.1080/15257770.2023.2234960. (IF= 1.3 in 2024)

2023

  1. Nagwa S.M. Aly, Hiroaki Matsumori, Thi Quyen Dinh, Akira Sato, Shin-Ich Miyoshi, Kyung-Soo Chang, Hak Sun Yu, Takaaki Kubota, Yuji Kurosaki, Duc Tuan Cao, Gehan A. Rashed, ＊Hye-Sook Kim. Evaluating the activity of N-89 as an oral antimalarial drug. Parasites, Hosts and Diseases, 61(3), 282-291, 2023. https//doi.org/10.3347/PHD.23044. (IF=1.776 in 2021)
  2. ＊Akira Sato, Akira Shimotsuma, Tetsuya Miyoshi, Yui Takahashi, Naoki Funayama, Yoko Ogino, Akiko Hiramoto, Yusuke Wataya, Hye-Sook Kim. Extracellular leakage protein patterns in two types of cancer cell death: necrosis and apoptosis. ACS Omega, 8(28), 25059-25065, 2023. http://doi.org/10.1021/acsomega.3c01691. (IF= 4.1, CiteScore=5.9 in 2022)
  3. Tomoyuki Abe, ＊Hiroshi Sakagami, Shigeru Amano, Shin Uota, Kenjiro Bandow, Yoshihiro Uesawa, Shiori U, Hiroki Shibata, Yuri Takemura, Yu Kimura, Koichi Takao, Yoshiaki Sugita, Akira Sato, Sei-ichi Tanuma, Hiroshi Takeshima. A Comparative Study of Tumor-Specificity and Neurotoxicity between 3-Styrylchromones and Anticancer Drugs. Medicines, 10(7), 43, 2023. https://doi.org/10.3390/medicines10070043. (IF = N.D. in 2021)
  4. #Chinatsu Kurasaka, #Nana Nishizawa, Haruka Uozumi, Yoko Ogino, ＊Akira Sato. Relationship between anticancer sensitivity and cellular respiration property in 5-fluorouracil-resistant HCT116 human colorectal cancer cells. FEBS OpenBio, 13 (6), 1125-1133, 2023. https://doi.org/10.1002/2211-5463.13611. (IF=2.792 in 2021) # equally contribution.
  5. Nagwa S. M. Aly, Hiroaki Matsumori, Thi Quyen Dinh, Akira Sato, Shin-Ich Miyoshi, Kyung-Soo Chang, Hak Sun Yu, Duc Tuan Cao, ＊Hye-Sook Kim. A pioneer use of antimalarial transdermal combination therapy in the rodent malaria model. Pathogens, 12(3), 398, 2023. https://doi.org/10.3390/pathogens12030398. (IF=4.531 in 2021)
  6. Nagwa S.M. Aly, Hiroaki Matsumori, Thi Quyen Dinh, Akira Sato, Shin-Ich Miyoshi, Kyung-Soo Chang, Hak Sun Yu, Fumie Kobayashi, ＊Hye-Sook Kim. Antimalarial effect of synthetic endoperoxide on synchronized Plasmodium chabaudi infected mice. Parasites, Hosts and Diseases, 61(1), 33-41, 2023. https://doi.org/10.3347/PHD.22119. (IF=1.776 in 2021)
  7. Nagwa S.M. Aly, Hiroaki Matsumori, Thi Quyen Dinh, Akira Sato, Shin-Ich Miyoshi, Kyung-Soo Chang, Hak Sun Yu, ＊Hye-Sook Kim. Formulation and evaluation of the antimalarial N-89 as a transdermal drug candidate. Parasitology International, 93, 102720, 2023. https://doi.org/10.1016/j.parint.2022.102720. (IF=2.106 in 2021)
  8. Nana Nishizawa, Chinatsu Kurasaka, Yoko Ogino, ＊Akira Sato. Regulation of 5-fluorodeoxyuridine monophosphate-thymidylate synthase ternary complex levels by autophagy confers resistance to 5-fluorouracil. FASEB BioAdvances,5(1), 43-51, 2023. https://doi.org/10.1096/fba.2022-00099. (IF=2.7, CiteScore= 4.4 in 2022)
  9. Kaede Tsuda, Chinatsu Kurasaka, Yoko Ogino, ＊Akira Sato. Genomic and biological aspects of resistance to selective poly(ADP-ribose) glycohydrolase inhibitor PDD00017273 in human colorectal cancer cells. Cancer Reports, 6(2), e1709, 2023. https://doi.org/10.1002/cnr2.1709 (IF=1.7, CiteScore=2.3 in 2022)

2022

  1. Chinatsu Kurasaka, Nana Nishizawa, Yoko Ogino, ＊Akira Sato. Trapping of 5-fluorodeoxyuridine monophosphate by thymidylate synthase confers resistance to 5-fluorouracil. ACS Omega, 7(7), 6046-6052, 2022. http://doi.org/10.1021/acsomega.1c06394 (IF= 4.1, CiteScore=5.9 in 2022)
  2. ＊Akira Sato, Nozomi Tagai, Yoko Ogino, Haruka Uozumi, Shinpei Kawakami, Takayuki Yamamoto, Sei-ichi Tanuma, Hiroko Maruki-Uchida, Sadao Mori, and Minoru Morita. Passion fruit seed extract protects beta-amyloid-induced neuronal cell death in a differentiated human neuroblastoma SH-SY5Y cell model. Food Science & Nutrition, 10(5), 1461-1468, 2022. http://doi.org/10.1002/fsn3.2757 (IF= 3.9, CiteScore=6.7 in 2022)

2021

  1. Natsumi Ogawa, Shingo Nakajima, Kenya Tamada, Natsuki Yokoue, Haruki Tachibana, Miwa Okazawa, Takahiro Oyama, Hideaki Abe, Hiroaki Yamazaki, Atsushi Yoshimori, Akira Sato, Takanori Kamiya, Takehiko Yokomizo, Fumiaki Uchiumi, Takehiko Abe, ＊Sei-ichi Tanuma. Trimebutine suppresses Toll-like receptor 2/4/7/8/9 signaling pathways in macrophages. Archives of Biochemistry and Biophysics, 711, 109029, 2021. doi: https://doi.org/10.1016/j.abb.2021.109029 (IF=4.114 in 2021)
  2. ＊Akira Sato, Yoko Ogino, Sei-ichi Tanuma, Fumiaki Uchiumi. Human microRNA hsa-miR-15b-5p targets the RNA template component of the RNA-dependent RNA polymerase structure in severe acute respiratory syndrome coronavirus 2. Nucleosides, Nucleotides & Nucleic Acids, 40:8, 790-797, 2021. doi: 10.1080/15257770.2021.1950759 (IF=1.449 in 2021)
  3. Chinatsu Kurasaka, Yoko Ogino, ＊Akira Sato. Molecular mechanisms and tumor biological aspects of 5-fluorouracil resistance in HCT116 human colorectal cancer cells. International Journal of Molecular Sciences, 22(6), 2916, 2021. https://doi.org/10.3390/ijms22062916. (IF=6.208 in 2021)
  4. ＊Kazumi Yoshizawa, Kota Takeuchi, Toka Nakamura, Saki Ukai, Yukino Takahashi, Akira Sato, Ryoko Takasawa, Sei‐ichi Tanuma. Antinociceptive activity of the novel RAGE inhibitor, papaverine, in a mouse model of chronic inflammatory pain. Synapse, 75, e22188, 2021. https://doi.org/10.1002/syn.22188 (IF-2.537 in 2021)

2020

  1. ＊Akira Sato, Akihiro Yamamoto, Akira Shimotsuma, Yoko Ogino, Naoki Funayama, Yui Takahashi, Akiko Hiramoto, Yusuke Wataya, Hye-Sook Kim. Intracellular microRNA expression patterns influence cell death fates for both necrosis and apoptosis. FEBS Open Bio,10(11), 2417-2426, 2020. https://doi.org/10.1002/2211-5463.12995. (IF=2.321, CiteScore=3.0 in 2019)
  2. Shingo Nakajima, Natsumi Ogawa, Natsuki Yokoue, Haruki Tachibana, Kenya Tamada, Miwa Okazawa, Akira Sato, Takahiro Oyama, Hideaki Abe, Takanori Kamiya, Atsushi Yoshimori, Kazumi Yoshizawa, Shigeaki Inoue, Takehiko Yokomizo, Fumiaki Uchiumi, Takehiko Abe, ＊Sei-ichi Tanuma. Trimebutine attenuates high mobility group box 1–receptor for advanced glycation end-products inflammatory signaling pathways. Biochemical and Biophysical Research Communications, 533(4), 1155-1161, 2020. https://doi.org/10.1016/j.bbrc.2020.09.126. (IF=2.985, CiteScore=4.6 in 2019)
  3. ＊Akira Sato, Akiko Hiramoto, Hye-Sook Kim, Yusuke Wataya. Anticancer Strategy Targeting Cell Death Regulators: Switching the Mechanism of Anticancer Floxuridine-Induced Cell Death from Necrosis to Apoptosis. The International Journal of Molecular Sciences, 21(16), 5876, 2020. doi: 10.3390/ijms21165876 (IF=5.923 in 2020, CiteScore=5.3 in 2019) Review article
  4. ＊Sei-ichi Tanuma, Kiyotaka Katsuragi, Takahiro Oyama, Atsushi Yoshimori, Yuri Shibasaki, Yasunobu Asawa, Hiroaki Yamazaki, Kosho Makino, Miwa Okazawa, Yoko Ogino, Yoshimi Sakamoto, Miyuki Nomura, Akira Sato, Hideaki Abe, Hiroyuki Nakamura, Hideyo Takahashi, Nobuhiro Tanuma, Fumiaki Uchiumi. Structural basis of beneficial design for effective nicotinamide phosphoribosyltransferase inhibitors. Molecules, 25(16), 3633, 2020. doi: 10.3390/molecules25163633. (IF=3.267, CiteScore=4.1 in 2019)
  5. #Nozomi Tagai, #Ayako Tanaka, ＊Akira Sato, Fumiaki Uchiumi, ＊Sei-ichi Tanuma. Low levels of brain-derived neurotrophic factor trigger self-aggregated amyloid β-induced neuronal cell death in an Alzheimer’s cell model. Biological and Pharmaceutical Bulletin, 43(7), 1073-1080, 2020. doi: 10.1248/bpb.b20-00082.(IF=1.540, CiteScore=1.77 in 2018) # equally contribution.
  6. ＊Fumiaki Uchiumi, Yoko Ogino, Akira Sato, Sei-ichi Tanuma. Insights into the development of effective materials to suppress replication of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).  AIMS Bioengineering, 7(3), 124-129, 2020. doi: 10.3934/bioeng.2020012. Short communication
  7. ＊Fumiaki Uchiumi, Akira Sato, Masashi Asai, Sei-ichi Tanuma. An NAD+ dependent/sensitive transcription system: Toward a novel anti-cancer therapy. AIMS Molecular Science, 7(1) 12-28, 2020. doi: 10.3934/molsci.2020002. Review article
  8. ＊Akira Sato, Yoko Ogino, Akira Shimotsuma, Akiko Hiramoto, Hye-Sook Kim, Yusuke Wataya. Direct interaction analysis of microRNA-351-5p and nuclear scaffold lamin B1 mRNA by the cell-free in vitro mRNA/miRNA binding evaluation system. Nucleosides, Nucleotides and Nucleic Acids, 39(6), 799-805, 2020. doi: 10.1080/15257770.2019.1702675. (IF=1.556, CiteScore=2.2 in 2019)

2019

  1. Mana Inada, ＊Akira Sato, Mika Shindo, Yohei Yamamoto,  Yasuharu Akasaki, Koichi Ichimura, Sei-ichi Tanuma. Anti-cancer non-narcotic opium alkaloid papaverine suppresses human glioblastoma cell growth. Anticancer Research, 39(12), 6743-6750, 2019. doi: 10.21873/anticanres.13889. (IF=1.935, CiteScore=1.90 in 2018)
  2. Yoko Ogino, ＊Akira Sato, Yohei Kawano, Takao Aoyama, Fumiaki Uchiumi, Sei-ichi Tanuma. Association of ABC transporter with resistance to FK866, a NAMPT inhibitor, in human colorectal cancer cells. Anticancer Research, 39(12), 6457-6462, 2019. doi: 10.21873/anticanres.13859. (IF=1.935, CiteScore=1.90 in 2018)
  3. Yoko Ogino, ＊Akira Sato, Fumiaki Uchiumi, Sei-ichi Tanuma. Genomic and tumor biological aspects of the anticancer nicotinamide phosphoribosyltransferase inhibitor FK866 in resistant human colorectal cancer cells. Genomics, 111(6), 1889-1895, 2019. doi: 10.1016/j.ygeno.2018.12.012 (IF=6.205, CiteScore=5.50 in 2019)
  4. Hiroshi Hamada, Yuta Goto, Jun Arakawa, Erisa Murayama, Yui Ogawa, Midori Konno, Takahiro Oyama, Masashi Asai, Akira Sato, Sei-ichi Tanuma, ＊Fumiaki Uchiumi. Characterization of the human E2F4 promoter region and its response to 12-O-tetradecanoylphorbol-13-acetate. The Journal of Biochemistry, 166 (4), 363-373, 2019. doi: https://doi.org/10.1093/jb/mvz047 (IF=2.230, CiteScore=2.33 in 2018)
  5. ＊Takayuki Yamamoto, Akira Sato, Yusuke Takai, Atsushi Yoshimori, Masahiro Umehara, Yoko Ogino, Mana Inada, Nami Shimada, Aya Nishida, Risa Ichida, Ryoko Takasawa, Hiroko Maruki-Uchida, Sadao Mori, Masahiko Sai, Minoru Morita, ＊Sei-ichi Tanuma. Effect of piceatannol-rich passion fruitseed extract on human glyoxalase I-mediated cancer cell growth. Biochemistry and Biophysics Reports, 20, 100684, 2019. https://doi.org/10.1016/j.bbrep.2019.100684 (CiteScore=3.6 in 2019)
  6. Masayuki Morita, Kosuke Hayashi, Akira Sato, Akiko Hiramoto, Osamu Kaneko, Rena Isogawa, Yuji Kurosaki, Shin-ichi Miyoshi, Kyung-Soo Chang, Yusuke Wataya, ＊Hye-Sook Kim. Genomic and biological features of Plasmodium falciparum resistance against antimalarial endoperoxide N-89. Gene, 716, 144016, 2019. doi: https://doi.org/10.1016/j.gene.2019.144016 (IF=2.984, CiteScore=4.8 in 2019)
  7. Kazuaki Okada, Akira Sato, Akiko Hiramoto, Rena Isogawa, Yuji Kurosaki, ＊Kazutaka Higaki, Shin-Ichi Miyoshi, Kyung-Soo Chang, ＊Hye-Sook Kim. Pharmacokinetic analysis of new synthetic antimalarial N-251. Tropical Medicine and Health, 47:40, 2019. https://doi.org/10.1186/s41182-019-0167-4. (SJR=0.563, CiteScore=1.130 in 2017)
  8. Yasunobu Asawa, Kiyotaka Katsuragi, Akira Sato, Atsushi Yoshimori, ＊Sei-ichi Tanuma, ＊Hiroyuki Nakamura. Structure-based drug design of novel carborane-containing nicotinamide phosphoribosyltransferase inhibitors. Bioorganic & Medicinal Chemistry, 27(13), 2832-2844, 2019. doi: 10.1016/j.bmc.2019.05.013. (IF=3.073, CiteScore=5.5 in 2019)
  9. Mana Inada, Mika Shindo, Kyousuke Kobayashi, ＊Akira Sato, Yohei Yamamoto,  Yasuharu Akasaki, Koichi Ichimura, ＊Sei-ichi Tanuma. Anticancer effects of a non-narcotic opium alkaloid medicine papaverine in human glioblastoma cells. PLOS ONE, 14(5):e0216358, 2019. https://doi.org/10.1371/journal.pone.0216358 (IF=2.766, CiteScore=5.2 in 2019)
  10. Kenya Tamada, Shingo Nakajima, Natsumi Ogawa, Mana Inada, Hiroyuki Shibasaki, Akira Sato, Ryoko Takasawa, Atsushi Yoshimori, Yusuke Suzuki, Nobuo Watanabe, Takahiro Oyama, Hideaki Abe, Shigeaki, Inoue, Takehiko Abe, Takehiko Yokomizo, ＊Sei-ichi Tanuma. Papaverine identified as an inhibitor of high mobility group box 1/receptor for advanced glycation end-products interaction suppresses high mobility group box 1-mediated inflammatory responses. Biochemical and Biophysical Research Communications, 511(3), 665-670, 2019. doi: 10.1016/j.bbrc.2019.01.136 (IF=2.985, CiteScore=4.60 in 2019)
  11. Hitoshi Tsugawa, Hideki Mori, Juntaro Matsuzaki, Akira Sato, Yoshimasa Saito, Masayo Imoto, Makoto Suematsu, ＊Hidekazu Suzuki. CAPZA1 determines the risk of gastric carcinogenesis by inhibiting Helicobacter pylori CagA-degraded autophagy. Autophagy, 15(2), 242-258, 2019. doi:10.1080/15548627.2018.1515530. (IF=9.770, CiteScore=17.9 in 2019)

2018

  1. Emmanuel Awusah Blay, Takashi Kumagai, Masafumi Yamabe, Akina Hino, Rieko Shimogawara, Hye-Sook Kim, Akira Sato, Koichiro Ichimura, Irene Ayi, Shiroh Iwanaga, ＊Nobuo Ohta. Insights into the mode of action of 1,2,6,7-tetraoxaspiro [7.11] nonadecane (N-89) against adult Schistosoma mansoni worms. Parasitology International, 67(4), 403-412, 2018. doi: 10.1016/j.parint.2018.03.006.(IF=2.055, 2017; CiteScore=1.87, 2017)
  2. Yoko Ogino, ＊Akira Sato, Fumiaki Uchiumi, ＊Sei-ichi Tanuma. Cross resistance to diverse anticancer nicotinamide phosphoribosyltransferase inhibitors induced by FK866 treatment. Oncotarget, 9(23), 16451-16461, 2018. doi: 10.18632/oncotarget.24731. (IF=5.168, 2016; CiteScore=4.65, 2017)
  3. Aly Hafez Ali Mohammed El-Far, Seiichi Munesue, Ai Harashima, Akira Sato, Mika Shindo, Shingo Nakajima, Mana Inada, Mariko Tanaka, Akihiko Takeuchi, Hiroyuki Tsuchiya, Hiroshi Yamamoto, Hazem M.E. Shaheen, Yasser S. El-Sayed, Shuhei Kawano, Sei-ichi Tanuma, ＊Yasuhiko Yamamoto. In vitro anticancer effects of a RAGE inhibitor discovered using a structure-based drug design system. Oncology Letters, 15, 4627-4634, 2018. doi: 10.3892/ol.2018.7902. (IF=1.664, 2017; CiteScore=1.69, 2017)

2017

  1. ＊Akira Sato. Novel anticancer strategy targeting switch mechanisms on two types of cell death, necrosis or apoptosis. YAKUGAKU ZASSHI, 137(11), 1315-1321, doi: 10.1248/yakushi.17-00131. Review
  2. Min-Young Seo, ＊Jae-Sook Ryu, Akira Sato, Yuji Kurosaki, Kyung-Soo Chang. ＊Hye-Sook Kim. Potential of synthetic endoperoxides against Trichomonas vaginalis in vitro. Parasitology International, 66(5), 619-621, 2017. doi: 10.1016/j.parint.2017.05.008.
  3. ＊Akira Sato, Takeshi Takano, Akiko Hiramoto, Tomoharu Naito, Akira Matsuda, Masakazu Fukushima, Yusuke Wataya, ＊Hye-Sook Kim. Role of uridine/cytidine kinase 2 mutation in cellular sensitiveness toward 3’-ethynylcytidine-treatment of human cancer cells. Anti-Cancer Drugs, 28(7), 781-786, 2017. doi: 10.1097/CAD.0000000000000519.
  4. Takahiro Oyama, Atsushi Yoshimori, Satoshi Takahashi, Tetsuya Yamamoto, Akira Sato, Takanori Kamiya, Hideaki Abe, Takehiko Abe, ＊Sei-ichi Tanuma. Structural insight into the active site of mushroom tyrosinase using phenylbenzoic acid derivatives. Bioorganic & Medicinal Chemistry Letters, 27(13), 2868-2872, 2017. doi: 10.1016/j.bmcl.2017.04.074.
  5. Yosuke Hisamatsu, Nozomi Suzuki, Abdullah-Al Masum, Ai Shibuya, Ryo Abe, Akira Sato, Sei-ichi Tanuma, ＊Shin Aoki. Cationic amphiphilic tris-cyclometalated iridium(III) complexes induce cancer cell death via interaction with Ca2+-calmodulin complex. Bioconjugate Chemistry, 28(2), 507-523, 2017. doi: 10.1021/acs.bioconjchem.6b00627.
  6. Masafumi Yamabe, Takashi Kumagai, Rieko Shimogawara, Emmanuel Awusah Blay, Akina Hino, Koichiro Ichimura, Akira Sato, Hye-Sook Kim, ＊Nobuo Ohta. Novel synthetic compounds with endoperoxide structure damage juvenile stage of Schistosoma mansoni by targeting lysosome-like organelles. Parasitology International, 66(1), 917-924, 2017. doi: 10.1016/j.parint.2016.10.013.

2016

  1. Mika Shindo, Akira Sato, Yohei Yamamoto, Takao Arai, Yasuharu Akasaki, Koichi Ichimura, ＊Sei-ichi Tanuma. Establishing a screening system for new O6-methylguanine-DNA methyltransferase inhibitors to develop combination chemotherapy for temozolomide-resistant glioblastoma. Tokyo Jikeikai Medical Journal, 131(5), 141-147, 2016.
  2. Takahiro Oyama, Satoshi Takahashi, Atsushi Yoshimori, Tetsuya Yamamoto, Akira Sato, Takanori Kamiya, Hideaki Abe, Takehiko Abe, ＊Sei-ichi Tanuma. Discovery of a new type of scaffold for the creation of novel tyrosinase inhibitors. Bioorganic & Medicinal Chemistry, 24(18), 4509-4515, 2016. doi: 10.1016/j.bmc.2016.07.060.
  3. Chun-Feng Xin, Hye-Sook Kim, Akira Sato, Hak-Jae Lee, You-Won Lee, Kyoung-Ho Pyo, ＊Eun-Hee Shin. In vitro inhibition of Toxoplasma gondii by the anti-malarial candidate, 6-(1,2,6,7-tetraoxaspiro[11]nonadec-4-yl)hexan-1-ol. Parasitology International, 65(5, Part A), 494-499, 2016. doi: 10.1016/j.parint.2016.06.013.
  4. ＊Akira Sato, Takuya Omi,  Akihiro Yamamoto, Akito Satake, Akiko Hiramoto, Mitsuko Masutani, Sei-ichi Tanuma, Yusuke Wataya, Hye-Sook Kim. MicroRNA-351 regulates two-types of cell death, necrosis and apoptosis, induced by 5-fluoro-2’-deoxyuridine. PLOS ONE,11(4): e0153130, 2016. doi:10.1371/journal.pone.0153130
  5. ＊Sei-ichi Tanuma, Akira Sato, Takahiro Oyama, Atsushi Yoshimori, Hideaki Abe, Fumiaki Uchiumi. New Insights into the Roles of NAD+-Poly(ADP-ribose) Metabolism and Poly(ADP-ribose) Glycohydrolase. Current Protein & Peptide Science, 17(7), 668-682, 2016. doi: 10.2174/1389203717666160419150014. Review

2015

  1. ＊Hye-Sook Kim, Akane Katamoto, Akira Sato, Yusuke Wataya, Hiroyuki Doi. New antimalarial endoperoxides for drug-resistant Plasmodium falciparum: The current situation. Okayama Igakkai Zasshi (Journal of Okayama Medical Association), 127, 231-235, 2015. doi: 10.4044/joma.127.231. Review
  2. Hiroaki Fujimori, Akira Sato, Sota Kikuhara, Junhui Wang, Takahisa Hirai, Yuka Sasaki, Yasufumi Murakami, Ryuichi Okayasu, ＊Mitsuko Masutani. A comprehensive analysis of radiosensitization targets; functional inhibition of DNA methyltransferase 3B radiosensitizes by disrupting DNA damage responses. Scientific Reports, 5, 18231, 2015. Doi: 10.1038/srep18231
  3. ＊Hiroshi Sakagami, Chiyako Shimada, Yumiko Kanda, Osamu Amano, Masahiro Sugimoto, Sana Ota, Tomoyoshi Soga, Masaru Tomita, Akira Sato, Sei-ichi Tanuma, Koichi Takao, Yoshiaki Sugita. Effects of 3-styrylchromones on metabolic profiles and cell death in oral squamous cell carcinoma cells. Toxicology Reports, 2, 1281-1290, 2015. doi:10.1016/j.toxrep.2015.09.009
  4. Akira Sato, Tasuku Itoh, Shoji Imamichi, Sota Kikuhara, Hiroaki Fujimori, Takahisa Hirai, Soichiro Saito, Yoshinori Sakurai, Hiroki Tanaka, Hiroyuki Nakamura, Minoru Suzuki, Yasufumi Murakami, Diaz Baiseitov, Kulzhan Berikkhanova, Zhaxybay Zhumadilov, Yoshio Imahori, Jun Itami, Koji Ono, Shinichiro Masunaga, ＊Mitsuko Masutani. Proteomic analysis of cellular response induced by boron neutron capture reaction in human squamous cell carcinoma SAS cells. Applied Radiation and Isotopes, 106, 113-219, 2015. doi: 10.1016/j.apradiso.2015.08.001.
  5. Chikako Imada, Takuma Takahashi, Makoto Kuramoto, Kazufumi Masuda, Ken-Ichi Ogawara, Akira Sato, Yusuke Wataya, Hye-Sook Kim, ＊Kazutaka Higaki. Improvement of Oral Bioavailability of N-251, a Novel Antimalarial Drug, by Increasing Lymphatic Transport with Long-chain Fatty Acid-based Self-nanoemulsifying Drug Delivery System, Pharmaceutical Research 32, 2595-2608, 2015. doi: 10.1007/s11095-015-1646-x.
  6. Masayuki Morita, Takahiro Koyama, Hitomi Sanai, Akira Sato, Akiko Hiramoto, Araki Masuyama, Masatomo Nojima, Yusuke Wataya, ＊Hye-Sook Kim. Stage specific activity of synthetic antimalarial endoperoxides, N-89 and N-251, against Plasmodium falciparum. Parasitology International 64, 113-117, 2015. doi: 10.1016/j.parint.2014.10.007.

2014

  1. ＊Akira Sato, Kentaro Nakama, Hiroki Watanabe, Akito Satake, Akihiro Yamamoto, Akiko Hiramoto, Mitsuko Masutani, Yusuke Wataya, ＊Hye-Sook Kim. Role of Activating Transcription Factor 3 Protein ATF3 in Necrosis and Apoptosis Induced by 5-Fluoro-2′-deoxyuridine. The FEBS Journal 281, 1892-1900, 2014. doi: 10.1111/febs.12752.

2013

  1. Youki Ueda, Midori Takeda, Kyoko Mori, Hiromichi Dansako, Takaji Wakita, Hye-Sook Kim, Akira Sato, Yusuke Wataya, Masanori Ikeda, ＊Nobuyuki Kato. New preclinical antimalarial drugs potently inhibit hepatitis C virus genotype 1b RNA replication. PLOS ONE 8, e72519, 2013. doi: 10.1371/journal.pone.0072519.

2012

  1. Masayuki Morita, Hitomi Sanai, Akiko Hiramoto, Akira Sato, Osamu Hiraoka, Takaya Sakura, Osamu Kaneko, Araki Masuyama, Masatomo Nojima, Yusuke Wataya, ＊Hye-Sook Kim. Plasmodium falciparum endoplasmic reticulum-resident calcium binding protein is a possible target of synthetic antimalarial endoperoxides, N-89 and N-251. Journal of Proteome Research 11, 5704-5711, 2012. doi: 10.1021/pr3005315.
  2. Yuji Tanaka, Asami Sakamoto, Takanobu Inoue, Takeshi Yamada, Takashi Kikuchi, Tetsuya Kajimoto, Osamu Muraoka, Akira Sato, Yusuke Wataya, Hye-Sook Kim, ＊Reiko Tanaka. Andirolides H-P from the flower of andiroba (Carapa guianensis, Meliaceae). Tetrahedron 68, 3669-3677, 2012. doi: https://doi.org/10.1016/j.tet.2011.12.076.

2011

  1. Akira Sato, Satoru Kawai, Akiko Hiramoto, Masayuki Morita, Natsuki Tanigawa, Yukari Nakase, Yuka Komichi, Masahiro Matsumoto, Osamu Hiraoka, Kazuyuki Hiramoto, Hidekazu Tokuhara, Araki Masuyama, Masatomo Nojima, Kazutaka Higaki, Hikoya Hayatsu, Yusuke Wataya, ＊Hye-Sook Kim. Antimalarial Activity of 6-(1,2,6,7-Tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol (N-251) and Its Carboxylic Acid Derivatives. Parasitology International 60, 488-492, 2011. doi: 10.1016/j.parint.2011.08.017.
  2. Akira Sato, Akiko Hiramoto, Masayuki Morita, Masahiro Matsumoto, Yuka Komichi, Yukari Nakase, Natsuki Tanigawa, Osamu Hiraoka, Kazuyuki Hiramoto, Hikoya Hayatsu, Kazutaka Higaki, Satoru Kawai, Araki Masuyama, Masatomo Nojima, Yusuke Wataya, ＊Hye-Sook Kim. Antimalarial Activity of Endoperoxide Compound 6-(1,2,6,7-Tetraoxaspiro[7.11]nonadec-4-yl)hexan-1-ol. Parasitology International 60, 270-273, 2011. doi: 10.1016/j.parint.2011.04.001.
  3. Toshie Taniguchi, Takashi Kumagai, Rieko Shimogawara, Shizuko Ichinose, Akiko Hiramoto, Akira Sato, Masayuki Morita, Masatomo Nojima, Hye-Sook Kim, Yusuke Wataya, ＊Nobuo Ohta. Schistosomicidal and antifecundity effects of oral treatment of synthetic endoperoxide N-89. Parasitology International 60, 231-236, 2011. doi: 10.1016/j.parint.2011.02.007.

2010

  1. Akiko Sato, Tomoharu Naito, Akiko Hiramoto, Kazato Goda, Takuya Omi, Yukio Kitade, Takuma Sasaki, Akira Matsuda, Masakazu Fukushima, Yusuke Wataya, ＊Hye-Sook Kim. Association of RNase L with a Ras GTPase-activating-like protein IQGAP1 in mediating the apoptosis of a human cancer cell-line. The FEBS Journal 277, 4464-4473, 2010. doi: 10.1111/j.1742-4658.2010.07833.x.
  2. Akira Sato, Akito Satake, Akiko Hiramoto, Yusuke Wataya, ＊Hye-Sook Kim. Protein expression profiles of necrosis and apoptosis induced by 5-fluoro-2’-deoxyuridine in mouse cancer cells.  Journal of Proteome Research 9, 2329-2338, 2010. doi: 10.1021/pr9010537.

2009

  1. Tomoharu Naito, Tatsushi Yokogawa, Satoshi Takatori, Kazato Goda, Akiko Hiramoto, Akira Sato, Yukio Kitade, Takuma Sasaki, Akira Matsuda, Masakazu Fukushima, Yusuke Wataya, ＊Hye-Sook Kim. Role of RNase L in apoptosis induced by 1-(3-C-ethynyl-beta-D-ribo-pentofuranosyl)cytosine. Cancer Chemotherapy and Pharmacology 63, 837-850, 2009. doi: 10.1007/s00280-008-0810-y.

2008

  1. Akira Sato, Akiko Hiramoto, Yusuke Uchikubo, Eriko Miyazaki, Akito Satake, Tomoharu Naito, Osamu Hiraoka, Tsuyoshi Miyake, Hye-Sook Kim, ＊Yusuke Wataya. Gene expression profiles of necrosis and apoptosis induced by 5-fluoro-2′-deoxyuridine. Genomics 92, 9-17, 2008. doi: 10.1016/j.ygeno.2008.02.002.
  2. Akira Sato, Akiko Hiramoto, Akito Satake, Eriko Miyazaki, Tomoharu Naito, Yusuke Wataya, ＊Hye-Sook Kim. Association of nuclear membrane protein lamin B1 with necrosis and apoptosis in cell death induced by 5-fluoro-2′-deoxyuridine. Nucleosides, Nucleotides & Nucleic Acids 27, 433-438, 2008. doi: 10.1080/15257770802086864.
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